Optimal design and validation of antiviral siRNA for targeting HIV-1
<p>Abstract</p> <p>We propose rational designing of antiviral short-interfering RNA (siRNA) targeting highly divergent HIV-1. In this study, conserved regions within HIV-1 genomes were identified through an exhaustive computational analysis, and the functionality of siRNAs targetin...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-11-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/4/1/80 |