Relationship between Structure and Antibacterial Activity of α-Aminophosphonate Derivatives Obtained via Lipase-Catalyzed Kabachnik−Fields Reaction

Relationship between Structure and Antibacterial Activity of α-Aminophosphonate Derivatives Obtained via Lipase-Catalyzed Kabachnik−Fields Reaction

We reported a new method dealing with the synthesis of novel pharmacologically relevant α-aminophosphonate derivatives via a lipase-catalyzed Kabachnik−Fields reaction with yields of up to 93%. The advantages of this protocol are excellent yields, mild reaction conditions, low costs, and sustainabil...

Full description

Bibliographic Details
Main Authors: Dominik Koszelewski, Paweł Kowalczyk, Paweł Śmigielski, Jan Samsonowicz-Górski, Karol Kramkowski, Aleksandra Wypych, Mateusz Szymczak, Ryszard Ostaszewski
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Materials
Subjects:
α-aminophosphonates
Kabachnik−Fields reaction
antimicrobial activity
Online Access:https://www.mdpi.com/1996-1944/15/11/3846

Internet

https://www.mdpi.com/1996-1944/15/11/3846

Similar Items