Analysis of common genetic variation across targets of microRNAs dysregulated both in ASD and epilepsy reveals negative correlation

Analysis of common genetic variation across targets of microRNAs dysregulated both in ASD and epilepsy reveals negative correlation

Genetic overlap involving rare disrupting mutations may contribute to high comorbidity rates between autism spectrum disorders and epilepsy. Despite their polygenic nature, genome-wide association studies have not reported a significant contribution of common genetic variation to comorbidity between...

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Bibliographic Details
Main Authors: Carol Stella, Covadonga M. Díaz-Caneja, Maria Jose Penzol, Alicia García-Alcón, Andrea Solís, Álvaro Andreu-Bernabeu, Xaquín Gurriarán, Celso Arango, Mara Parellada, Javier González-Peñas
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Genetics
Subjects:
autism
epilepsy
microRNA
comorbidity
genetic correlation
genetic heterogeneity
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1072563/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1072563/full

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