Mechanobiological responses of astrocytes in optic nerve head due to biaxial stretch

Mechanobiological responses of astrocytes in optic nerve head due to biaxial stretch

Abstract Background Elevated intraocular pressure (IOP) is the main risk factor for glaucoma, which might cause the activation of astrocytes in optic nerve head. To determine the effect of mechanical stretch on the astrocytes, we investigated the changes in cell phenotype, proteins of interest and s...

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Bibliographic Details
Main Authors: Zhiwen Li, Fan Peng, Zhicheng Liu, Shanshan Li, Lin Li, Xiuqing Qian
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Ophthalmology
Subjects:
Astrocytes
Biaxial stretch
Mechanobiological responses
Proteomics
Optic nerve head
Online Access:https://doi.org/10.1186/s12886-022-02592-8

Internet

https://doi.org/10.1186/s12886-022-02592-8

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