Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition

Abstract Background Core promoter controls transcription initiation. However, little is known for core promoter diversity in the human genome and its relationship with diseases. We hypothesized that as a functional important component in the genome, the core promoter in the human genome could be und...

Full description

Bibliographic Details
Main Authors: Hemant Gupta, Khyati Chandratre, Siddharth Sinha, Teng Huang, Xiaobing Wu, Jian Cui, Michael Q. Zhang, San Ming Wang
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-020-07222-5