Design and synthesis of fluorine aromatic scaffolds containing drugs approved by the US FDA from 2002 to 2022

Design and synthesis of fluorine aromatic scaffolds containing drugs approved by the US FDA from 2002 to 2022

There are totally 93 fluorine aromatic scaffolds containing drugs approved by U.S. Food and Drug Administration from 2002 to 2022. The proportion of drugs containing fluorinated aromatic skeleton in approved drugs is increasing in recent ten years, which indicates the unique and important attributes...

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Bibliographic Details
Main Authors: Pengfei Xu, Lijun Zhu, Desheng Zhang, Zilong Li, Raoling Ge, Qiang Tian
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Fluorine aromatic
FDA-approved drugs
Clinical application
Chemical synthesis
Medicinal chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624001425

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http://www.sciencedirect.com/science/article/pii/S2211715624001425

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