2′-O-Methylation of Ribosomal RNA: Towards an Epitranscriptomic Control of Translation?
Ribosomal RNA (rRNA) undergoes post-transcriptional modification of over 200 nucleotides, predominantly 2′-O-methylation (2′-O-Me). 2′-O-Methylation protects RNA from hydrolysis and modifies RNA strand flexibility but does not contribute to Watson-Crick base pairing. Th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-273X/8/4/106 |