Triterpenic Acid Amides as a Promising Agent for Treatment of Metabolic Syndrome

Triterpenic Acid Amides as a Promising Agent for Treatment of Metabolic Syndrome

A series of triterpenic acid amides were synthesized incorporating a 2-ethoxy-3-phenylpropanoic acid pharmacophore fragment. The synthesized compounds were tested for their ability to improve glycemic control and to counter lipid abnormalities in C57BL/6 mice placed on a high-fat/high-cholesterol di...

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Bibliographic Details
Main Authors: Vladislav Fomenko, Mikhail Blokhin, Sergey Kuranov, Mikhail Khvostov, Dmitriy Baev, Marina S. Borisova, Olga Luzina, Tatyana G. Tolstikova, Nariman F. Salakhutdinov
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Scientia Pharmaceutica
Subjects:
type 2 diabetes mellitus
hypoglycemic activity
natural product
triterpenic amides
glucose tolerance
total cholesterol
Online Access:https://www.mdpi.com/2218-0532/89/1/4

Internet

https://www.mdpi.com/2218-0532/89/1/4

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