Disruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome

Disruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome

Abstract During mammalian spermatogenesis, the ubiquitin proteasome system maintains protein homoeostasis (proteastasis) and spermatogenic cellular functions. DCAF17 is a substrate receptor in the ubiquitin CRL4 E3 Ligase complex, absence of which causes oligoasthenoteratozoospermia in mice resultin...

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Bibliographic Details
Main Authors: Raed Abu-Dawud, Bhavesh V. Mistry, Mohamed Rajab, Maha Alanazi, Nadya Al-Yacoub, Junaid Kashir, Falah Almohanna, Dilek Colak, Abdullah M. Assiri
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25826-7

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https://doi.org/10.1038/s41598-022-25826-7

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