In Vivo Antidepressant Effect of <i>Passiflora edulis</i> f. <i>flavicarpa</i> into Cationic Nanoparticles: Improving Bioactivity and Safety

In Vivo Antidepressant Effect of <i>Passiflora edulis</i> f. <i>flavicarpa</i> into Cationic Nanoparticles: Improving Bioactivity and Safety

A variety of neuroactive flavonoids can be found in the species of the <i>Passiflora</i> genus; however, their difficulty in crossing the blood–brain barrier limits their in vivo neuropharmacological activity. In this study, cationic nanoparticles were developed as a novel nanocarrier fo...

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Bibliographic Details
Main Authors: Jovelina Samara Ferreira Alves, Alaine Maria dos Santos Silva, Rodrigo Moreira da Silva, Pamella Rebeca Fernandes Tiago, Thais Gomes de Carvalho, Raimundo Fernandes de Araújo Júnior, Eduardo Pereira de Azevedo, Norberto Peporine Lopes, Leandro De Santis Ferreira, Elaine Cristina Gavioli, Arnóbio Antônio da Silva-Júnior, Silvana Maria Zucolotto
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
flavonoids
nanotechnology
depression
oral toxicity
PMMA
Eudragit
Online Access:https://www.mdpi.com/1999-4923/12/4/383

Internet

https://www.mdpi.com/1999-4923/12/4/383

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