Bioengineered Wound Healing Skin Models: The Role of Immune Response and Endogenous ECM to Fully Replicate the Dynamic of Scar Tissue Formation In Vitro

Bioengineered Wound Healing Skin Models: The Role of Immune Response and Endogenous ECM to Fully Replicate the Dynamic of Scar Tissue Formation In Vitro

The healing of deep skin wounds is a complex phenomenon evolving according with a fine spatiotemporal regulation of different biological events (hemostasis, inflammation, proliferation, remodeling). Due to the spontaneous evolution of damaged human dermis toward a fibrotic scar, the treatment of dee...

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Bibliographic Details
Main Authors: Francesco Urciuolo, Roberta Passariello, Giorgia Imparato, Costantino Casale, Paolo Antonio Netti
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Bioengineering
Subjects:
scar tissue
engineered skin
skin on chip
wound healing
immune response
inflammation
Online Access:https://www.mdpi.com/2306-5354/9/6/233

Internet

https://www.mdpi.com/2306-5354/9/6/233

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