Targeting TGFβ signal transduction for cancer therapy

Abstract Transforming growth factor-β (TGFβ) family members are structurally and functionally related cytokines that have diverse effects on the regulation of cell fate during embryonic development and in the maintenance of adult tissue homeostasis. Dysregulation of TGFβ family signaling can lead to...

Full description

Bibliographic Details
Main Authors: Sijia Liu, Jiang Ren, Peter ten Dijke
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-020-00436-9