Systematic Quantification of Synapses in Primary Neuronal Culture

Systematic Quantification of Synapses in Primary Neuronal Culture

Summary: Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve synapse-oriented screens, we analyzed the labeling perf...

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Bibliographic Details
Main Authors: Peter Verstraelen, Gerardo Garcia-Diaz Barriga, Marlies Verschuuren, Bob Asselbergh, Rony Nuydens, Peter H. Larsen, Jean-Pierre Timmermans, Winnok H. De Vos
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Optical Imaging
Molecular Biology Experimental Approach
Cellular Neuroscience
Biocomputational Method
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307343

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http://www.sciencedirect.com/science/article/pii/S2589004220307343

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