Systematic Quantification of Synapses in Primary Neuronal Culture
Summary: Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve synapse-oriented screens, we analyzed the labeling perf...
Main Authors: | Peter Verstraelen, Gerardo Garcia-Diaz Barriga, Marlies Verschuuren, Bob Asselbergh, Rony Nuydens, Peter H. Larsen, Jean-Pierre Timmermans, Winnok H. De Vos |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
|
Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220307343 |
Similar Items
-
Integrated staging of morphofunctional connectivity in neuronal cultures
by: Peter Verstraelen, et al.
Published: (2024-06-01) -
Early classification of Alzheimer's disease phenotype based on hippocampal electrophysiology in the TgF344-AD rat model
by: Faraz Moradi, et al.
Published: (2023-08-01) -
Dysregulation of Microtubule Stability Impairs Morphofunctional Connectivity in Primary Neuronal Networks
by: Peter Verstraelen, et al.
Published: (2017-06-01) -
All-optical interrogation of brain-wide activity in freely swimming larval zebrafish
by: Yuming Chai, et al.
Published: (2024-01-01) -
Mixed Selectivity in Macaque Medial Parietal Cortex during Eye-Hand Reaching
by: Stefano Diomedi, et al.
Published: (2020-10-01)