Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

Summary: During development, hematopoietic stem and progenitor cells (HSPCs) arise from specialized endothelial cells by a process termed endothelial-to-hematopoietic transition (EHT). The genetic program driving human HSPC emergence remains largely unknown. We previously reported that the generatio...

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Main Authors: Andreia M. Gomes, Ilia Kurochkin, Betty Chang, Michael Daniel, Kenneth Law, Namita Satija, Alexander Lachmann, Zichen Wang, Lino Ferreira, Avi Ma’ayan, Benjamin K. Chen, Dmitri Papatsenko, Ihor R. Lemischka, Kateri A. Moore, Carlos-Filipe Pereira
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718317959

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http://www.sciencedirect.com/science/article/pii/S2211124718317959

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