Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice

Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice

Importin α3 (Gene: Kpna3, the ortholog of human Importin α4) is a member of the importin α family and participates in nucleocytoplasmic transport by forming trimeric complexes between cargo proteins and importin β1. Evidence from human studies has indicated that single nucleotide polymorphisms (SNP)...

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Bibliographic Details
Main Authors: Yoshiatsu Aomine, Koki Sakurai, Tom Macpherson, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Masahiro Oka, Takatoshi Hikida
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neuroscience
Subjects:
importin α
KPNA
progressive ratio schedule
c-fos
functional connectivity
brain network
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.905991/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.905991/full

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