A low-input high resolution sequential chromatin immunoprecipitation method captures genome-wide dynamics of bivalent chromatin
Abstract Background Bivalent chromatin is an exemplar of epigenetic plasticity. This co-occurrence of active-associated H3K4me3 and inactive-associated H3K27me3 histone modifications on opposite tails of the same nucleosome occurs predominantly at promoters that are poised for future transcriptional...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
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Series: | Epigenetics & Chromatin |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13072-024-00527-9 |