A low-input high resolution sequential chromatin immunoprecipitation method captures genome-wide dynamics of bivalent chromatin

Abstract Background Bivalent chromatin is an exemplar of epigenetic plasticity. This co-occurrence of active-associated H3K4me3 and inactive-associated H3K27me3 histone modifications on opposite tails of the same nucleosome occurs predominantly at promoters that are poised for future transcriptional...

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Bibliographic Details
Main Authors: Janith A. Seneviratne, William W. H. Ho, Eleanor Glancy, Melanie A. Eckersley-Maslin
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-024-00527-9