Cellular prion protein in the central nervous system of mammals. Anatomoclinical associations

Introduction: The scrapie prion protein (PrPsc) requieres the celular prion protein (PrPc) for its propagation and replication. In this work we studied the expression and localization of the PrPc in the central nervous system (SNC) of the rat, mouse, cat, cow and human, using immunohistochemistry an...

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Bibliographic Details
Main Authors: J.L. Velayos, A. Irujo, M. Cuadrado-Tejedor, B. Paternain, F.J. Moleres, V. Ferrer
Format: Article
Language:English
Published: Elsevier España 2010-01-01
Series:Neurología (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2173580810700468