The Emergence of Pan-Cancer CIMP and Its Elusive Interpretation
Epigenetic dysregulation is recognized as a hallmark of cancer. In the last 16 years, a CpG island methylator phenotype (CIMP) has been documented in tumors originating from different tissues. However, a looming question in the field is whether or not CIMP is a pan-cancer phenomenon or a tissue-spec...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-11-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-273X/6/4/45 |