Single-cell transcriptomic profile of human pulmonary artery endothelial cells in health and pulmonary arterial hypertension

Single-cell transcriptomic profile of human pulmonary artery endothelial cells in health and pulmonary arterial hypertension

Abstract Pulmonary arterial hypertension (PAH) is an insidious disease characterized by severe remodeling of the pulmonary vasculature caused in part by pathologic changes of endothelial cell functions. Although heterogeneity of endothelial cells across various vascular beds is well known, the diver...

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Bibliographic Details
Main Authors: Kewal Asosingh, Suzy Comhair, Lori Mavrakis, Weiling Xu, Dean Horton, Ian Taylor, Svyatoslav Tkachenko, Bo Hu, Serpil Erzurum
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94163-y

Internet

https://doi.org/10.1038/s41598-021-94163-y

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