Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice

Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice

There are currently no effective therapies available for acute kidney injury (AKI). Here the authors generate molybdenum-based polyoxometalate nanoclusters and show that these have preferential renal uptake and can ameliorate AKI pathology in mice by scavenging reactive oxygen species.

Bibliographic Details
Main Authors: Dalong Ni, Dawei Jiang, Christopher J. Kutyreff, Jianhao Lai, Yongjun Yan, Todd E. Barnhart, Bo Yu, Hyung-Jun Im, Lei Kang, Steve Y. Cho, Zhaofei Liu, Peng Huang, Jonathan W. Engle, Weibo Cai
Format: Article
Language:English
Published: Nature Portfolio 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07890-8

Internet

https://doi.org/10.1038/s41467-018-07890-8

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