Alignment of Skeletal Muscle Cells Facilitates Acetylcholine Receptor Clustering and Neuromuscular Junction Formation with Co-Cultured Human iPSC-Derived Motor Neurons

Alignment of Skeletal Muscle Cells Facilitates Acetylcholine Receptor Clustering and Neuromuscular Junction Formation with Co-Cultured Human iPSC-Derived Motor Neurons

In vitro neuromuscular junction (NMJ) models are powerful tools for studying neuromuscular disorders. Although linearly patterned culture surfaces have been reported to be useful for the formation of in vitro NMJ models using mouse motor neuron (MNs) and skeletal muscle (SkM) myotubes, it is unclear...

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Bibliographic Details
Main Authors: Kazunori Shimizu, Haruo Kassai, Yuhei Kamei, Kazuki Yamamoto, Takunori Nagashima, Tadayoshi Maekawa, Hirokazu Akiyama, Hiroyuki Honda
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
skeletal muscle
motor neuron
co-culture
micropatterns
Online Access:https://www.mdpi.com/2073-4409/11/23/3760

Internet

https://www.mdpi.com/2073-4409/11/23/3760

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