Studying the Inflammatory Responses to Amyloid Beta Oligomers in Brain-Specific Pericyte and Endothelial Co-Culture From Human Stem Cells

Studying the Inflammatory Responses to Amyloid Beta Oligomers in Brain-Specific Pericyte and Endothelial Co-Culture From Human Stem Cells

Background: Recently, the in vitro blood–brain barrier (BBB) models derived from human pluripotent stem cells have been given extensive attention in therapeutics due to the implications they have with the health of the central nervous system. It is essential to create an accurate BBB model in vitro...

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Bibliographic Details
Main Authors: Mark Marzano, Xingchi Chen, Teal A. Russell, Angelica Medina, Zizheng Wang, Timothy Hua, Changchun Zeng, Xueju Wang, Qing-Xiang Sang, Hengli Tang, Yeoheung Yun, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Chemical Engineering
Subjects:
stem cell derived brain-specific cells
co-culture
human pluripotent stem cells
brain pericytes
brain endothelial cells
microfluidics
Online Access:https://www.frontiersin.org/articles/10.3389/fceng.2022.927188/full

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https://www.frontiersin.org/articles/10.3389/fceng.2022.927188/full

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