Untangling Macropore Formation and Current Facilitation in P2X7

Untangling Macropore Formation and Current Facilitation in P2X7

Macropore formation and current facilitation are intriguing phenomena associated with ATP-gated P2X7 receptors (P2X7). Macropores are large pores formed in the cell membrane that allow the passage of large molecules. The precise mechanisms underlying macropore formation remain poorly understood, but...

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Bibliographic Details
Main Authors: Federico Cevoli, Benoit Arnould, Francisco Andrés Peralta, Thomas Grutter
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
P2X7
current facilitation
ATP sensitization
macropore formation
Online Access:https://www.mdpi.com/1422-0067/24/13/10896

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https://www.mdpi.com/1422-0067/24/13/10896

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