Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of Orodispersible Tablets

Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of Orodispersible Tablets

The novelty in this study is the development of new orodispersible tablets containing nifedipine (NIF) as the active ingredient. Initially, the formation of inclusion complexes between nifedipine and two derivatives of beta-cyclodextrin, namely, hydroxypropyl-β-cyclodextrin (HP-β-CD) and methyl-β-cy...

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Bibliographic Details
Main Authors: Emma Adriana Ozon, Marian Novac, Daniela Gheorghe, Adina Magdalena Musuc, Mirela Adriana Mitu, Iulian Sarbu, Valentina Anuta, Adriana Rusu, Simona Petrescu, Irina Atkinson, Dumitru Lupuliasa
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceuticals
Subjects:
nifedipine
inclusion complexes
hydroxypropyl-β-cyclodextrin
methyl-β-cyclodextrin orodispersible tablets
Online Access:https://www.mdpi.com/1424-8247/15/8/993

Internet

https://www.mdpi.com/1424-8247/15/8/993

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