Quantification of Treatment Effect Modification on Both an Additive and Multiplicative Scale.

BACKGROUND:In both observational and randomized studies, associations with overall survival are by and large assessed on a multiplicative scale using the Cox model. However, clinicians and clinical researchers have an ardent interest in assessing absolute benefit associated with treatments. In older...

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Bibliographic Details
Main Authors: Nicolas Girerd, Muriel Rabilloud, Philippe Pibarot, Patrick Mathieu, Pascal Roy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4821587?pdf=render