Oxidative Stress in the Male Germline: A Review of Novel Strategies to Reduce 4-Hydroxynonenal Production

Oxidative Stress in the Male Germline: A Review of Novel Strategies to Reduce 4-Hydroxynonenal Production

Germline oxidative stress is intimately linked to several reproductive pathologies including a failure of sperm-egg recognition. The lipid aldehyde 4-hydroxynonenal (4HNE) is particularly damaging to the process of sperm-egg recognition as it compromises the function and the stability of several ger...

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Bibliographic Details
Main Authors: Jessica L. H. Walters, Geoffry N. De Iuliis, Brett Nixon, Elizabeth G. Bromfield
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Antioxidants
Subjects:
male fertility
oxidative stress
4-hydroxynonenal (4HNE)
arachidonate 15-lipoxygenase (ALOX15)
lipid peroxidation
reactive oxygen species (ROS)
Online Access:http://www.mdpi.com/2076-3921/7/10/132

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http://www.mdpi.com/2076-3921/7/10/132

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