Effects of photoperiod and food on glucose intolerance and subsequent ocular pathology in the fat sand rat

Abstract Type 2 diabetes mellitus (T2DM) and its ocular complications, such as cataract and diabetic retinopathy (DR) have been linked to circadian rhythm-disturbances. Using a unique diurnal animal model, the sand rat (Psammomys obesus) we examined the effect of circadian disruption by short photop...

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Bibliographic Details
Main Authors: Carmel Bilu, Neta Butensky, Amit Richter Malamud, Haim Einat, Paul Zimmet, Ofira Zloto, Hana Ziv, Noga Kronfeld-Schor, Vicktoria Vishnevskia-Dai
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44584-8