Structural insights into the effect of mutations in the spike protein of SARS-CoV-2 on the binding with human furin protein

Structural insights into the effect of mutations in the spike protein of SARS-CoV-2 on the binding with human furin protein

The SARS COV-2 and its variants are spreading around the world at an alarming speed, due to its higher transmissibility and the conformational changes caused by mutations. The resulting COVID-19 pandemic has imposed severe health consequences on human health. Several countries of the world including...

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Bibliographic Details
Main Authors: Muhammad Suleman, Muhammad Luqman, Dong-Qing Wei, Shahid Ali, Syed Shujait Ali, Abbas Khan, Haji Khan, Zafar Ali, Wajid Khan, Muhammad Rizwan, Naeem Ullah
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
SARS COV-2
Furin
Molecular docking
Molecular simulation
S-Protein
Mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023022909

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http://www.sciencedirect.com/science/article/pii/S2405844023022909

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