The impact of population demography and selection on the genetic architecture of complex traits.
Population genetic studies have found evidence for dramatic population growth in recent human history. It is unclear how this recent population growth, combined with the effects of negative natural selection, has affected patterns of deleterious variation, as well as the number, frequency, and effec...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4038606?pdf=render |