Improving thymus implantation for congenital athymia with interleukin‐7

Improving thymus implantation for congenital athymia with interleukin‐7

Abstract Objectives Thymus implantation is a recently FDA‐approved therapy for congenital athymia. Patients receiving thymus implantation develop a functional but incomplete T cell compartment. Our objective was to develop a mouse model to study clinical thymus implantation in congenital athymia and...

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Bibliographic Details
Main Authors: Hyunjung Min, Laura A Valente, Li Xu, Shane M O'Neil, Lauren R Begg, Joanne Kurtzberg, Anthony J Filiano
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical & Translational Immunology
Subjects:
primary immunodeficiency disorders
T cells
thymus
translational immunology
transplant immunology
Online Access:https://doi.org/10.1002/cti2.1475

Internet

https://doi.org/10.1002/cti2.1475

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