‘Social’ versus ‘asocial’ cells—dynamic competition flux balance analysis
Abstract In multicellular organisms cells compete for resources or growth factors. If any one cell type wins, the co-existence of diverse cell types disappears. Existing dynamic Flux Balance Analysis (dFBA) does not accommodate changes in cell density caused by competition. Therefore we here develop...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
|
Series: | npj Systems Biology and Applications |
Online Access: | https://doi.org/10.1038/s41540-023-00313-5 |