Mediator Complex Subunit 19 Promotes the Development of Hepatocellular Carcinoma by Regulating the AKT/mTOR Signaling Pathway

Mediator Complex Subunit 19 Promotes the Development of Hepatocellular Carcinoma by Regulating the AKT/mTOR Signaling Pathway

BackgroundHepatocellular carcinoma (HCC) is one of the most common malignant tumors, the pathogenesis of which remains unclear. Mediator complex subunit 19 (MED19), a subunit of the Mediator complex, is a multi-protein co-activator necessary for DNA transcription factors to induce RNA polymerase II...

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Bibliographic Details
Main Authors: Yuting Zhang, Peifang Qin, Xingfeng Xu, Mao Li, Haitao Huang, Jianguo Yan, Yali Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
MED19
AKT/mTOR signaling pathway
proliferation/migration/invasion
tumor immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.792285/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.792285/full

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