The effect of dosage on the protective efficacy of whole-sporozoite formulations for immunization against malaria
Abstract Immunization with Plasmodium sporozoites, either attenuated or administered under the cover of an antimalarial drug, can induce strong protection against malaria in pre-clinical murine models, as well as in human trials. Previous studies have suggested that whole-sporozoite (WSpz) formulati...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-11-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-023-00778-9 |