Vanadium Pentoxide Exposure Causes Strain-Dependent Changes in Mitochondrial DNA Heteroplasmy, Copy Number, and Lesions, but Not Nuclear DNA Lesions

Vanadium Pentoxide Exposure Causes Strain-Dependent Changes in Mitochondrial DNA Heteroplasmy, Copy Number, and Lesions, but Not Nuclear DNA Lesions

Interstitial lung diseases (ILDs) are lethal lung diseases characterized by pulmonary inflammation and progressive lung interstitial scarring. We previously developed a mouse model of ILD using vanadium pentoxide (V<sub>2</sub>O<sub>5</sub>) and identified several gene candid...

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Bibliographic Details
Main Authors: Nick L. Dobson, Steven R. Kleeberger, Adam B. Burkholder, Dianne M. Walters, Wesley Gladwell, Kevin Gerrish, Heather L. Vellers
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial sequencing
mtDNA copy number
mtDNA damage
heteroplasmy
vanadium pentoxide
Online Access:https://www.mdpi.com/1422-0067/24/19/14507

Internet

https://www.mdpi.com/1422-0067/24/19/14507

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