Future Approaches for Treating Chronic Myeloid Leukemia: CRISPR Therapy

The constitutively active tyrosine-kinase <i>BCR/ABL1</i> oncogene plays a key role in human chronic myeloid leukemia development and disease maintenance, and determines most of the features of this leukemia. For this reason, tyrosine-kinase inhibitors are the first-line treatment, offer...

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Bibliographic Details
Main Authors: Elena Vuelta, Ignacio García-Tuñón, Patricia Hernández-Carabias, Lucía Méndez, Manuel Sánchez-Martín
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/2/118