CommPath: An R package for inference and analysis of pathway-mediated cell-cell communication chain from single-cell transcriptomics

CommPath: An R package for inference and analysis of pathway-mediated cell-cell communication chain from single-cell transcriptomics

Single-cell transcriptomics offers opportunities to investigate ligand-receptor (LR) interactions between heterogeneous cell populations within tissues. However, most existing tools for the inference of intercellular communication do not allow prioritization of functional LR associations that provok...

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Bibliographic Details
Main Authors: Hao Lu, Jie Ping, Guangming Zhou, Zhen Zhao, Weiming Gao, Yuqing Jiang, Cheng Quan, Yiming Lu, Gangqiao Zhou
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Cell-cell communication
Ligand-receptor interaction
scRNA-seq
R
Webserver
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022004755

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http://www.sciencedirect.com/science/article/pii/S2001037022004755

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