The microRNA-455 Null Mouse Has Memory Deficit and Increased Anxiety, Targeting Key Genes Involved in Alzheimer’s Disease

The microRNA-455 Null Mouse Has Memory Deficit and Increased Anxiety, Targeting Key Genes Involved in Alzheimer’s Disease

The complete molecular mechanisms underlying the pathophysiology of Alzheimer’s disease (AD) remain to be elucidated. Recently, microRNA-455-3p has been identified as a circulating biomarker of early AD, with increased expression in post-mortem brain tissue of AD patients. MicroRNA-455-3p also direc...

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Bibliographic Details
Main Authors: Tracey E. Swingler, Lingzi Niu, Matthew G. Pontifex, David Vauzour, Ian M. Clark
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
microRNA
miR-455
knockout
<i>APP</i>
<i>TAU</i>
Online Access:https://www.mdpi.com/1422-0067/23/1/554

Internet

https://www.mdpi.com/1422-0067/23/1/554

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