Integrative pharmacogenomics revealed three subtypes with different immune landscapes and specific therapeutic responses in lung adenocarcinoma

Integrative pharmacogenomics revealed three subtypes with different immune landscapes and specific therapeutic responses in lung adenocarcinoma

Background: Pharmacogenomics is crucial for individualized drug therapy and plays an increasingly vital role in precision medicine decision-making. However, pharmacogenomics-based molecular subtypes and their potential clinical significance remain primarily unexplored in lung adenocarcinoma (LUAD)....

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Bibliographic Details
Main Authors: Xiaoyong Ge, Zaoqu Liu, Siyuan Weng, Hui Xu, Yuyuan Zhang, Long Liu, Qin Dang, Chunguang Guo, Richard Beatson, Jinhai Deng, Xinwei Han
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Lung adenocarcinoma
Pharmacogenomics
Molecular subtypes
Immune landscapes
Precision medication
Therapeutic responses
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002781

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http://www.sciencedirect.com/science/article/pii/S2001037022002781

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