A novel murine model of combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma

A novel murine model of combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma

Abstract Primary liver cancer (PLC) is a common gastrointestinal malignancy worldwide. While hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are two major pathologic types of PLC, combined HCC and ICC (cHCC-ICC) is a relatively rare subtype that shares both hepatocyte and ch...

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Bibliographic Details
Main Authors: Ru-Chen Xu, Fu Wang, Jia-Lei Sun, Weinire Abuduwaili, Guang-Cong Zhang, Zhi-Yong Liu, Tao-Tao Liu, Ling Dong, Xi-Zhong Shen, Ji-Min Zhu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Translational Medicine
Subjects:
Myc
AKT1
p53
LAMB1
Sleeping Beauty-dependent transposon system
In situ electroporation
Online Access:https://doi.org/10.1186/s12967-022-03791-z

Internet

https://doi.org/10.1186/s12967-022-03791-z

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