Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential
Abstract Mitochondrial dysfunction is strongly implicated in the etiology of idiopathic and genetic Parkinson’s disease (PD). However, strategies aimed at ameliorating mitochondrial dysfunction, including antioxidants, antidiabetic drugs, and iron chelators, have failed in disease-modification clini...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-11-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13024-023-00676-7 |