Ameliorations in dyslipidemia and atherosclerotic plaque by the inhibition of HMG-CoA reductase and antioxidant potential of phytoconstituents of an aqueous seed extract of Acacia senegal (L.) Willd in rabbits.

The assigned work was aimed to examine the capability of phytoconstituents of an aqueous seed extract of Acacia senegal (L.) Willd to inhibit HMG-CoA reductase and regression of the atherosclerotic plaque. The chemical fingerprinting of the test extract was assessed by LC-MS/MS. Consequently, the an...

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Main Authors: Jaykaran Charan, Priyanka Riyad, Heera Ram, Ashok Purohit, Sneha Ambwani, Priya Kashyap, Garima Singh, Abeer Hashem, Elsayed Fathi Abd Allah, Vijai Kumar Gupta, Ashok Kumar, Anil Panwar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0264646