Molecular Evolutionary Analyses of the RNA-Dependent RNA Polymerase Region in Norovirus Genogroup II

Molecular Evolutionary Analyses of the RNA-Dependent RNA Polymerase Region in Norovirus Genogroup II

Noroviruses are the leading cause of viral gastroenteritis in humans across the world. RNA-dependent RNA polymerase (RdRp) plays a critical role in the replication of the viral genome. Although there have been some reports on a limited number of genotypes with respect to the norovirus evolution of t...

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Bibliographic Details
Main Authors: Keita Ozaki, Yuki Matsushima, Koo Nagasawa, Takumi Motoya, Akihide Ryo, Makoto Kuroda, Kazuhiko Katayama, Hirokazu Kimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
molecular evolution
norovirus
GII
bioinformatics
RNA-dependent RNA polymerase
negative selection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03070/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03070/full

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