Intradermal Immunization of Soluble Influenza HA Derived from a Lethal Virus Induces High Magnitude and Breadth of Antibody Responses and Provides Complete Protection In Vivo

Intradermal Immunization of Soluble Influenza HA Derived from a Lethal Virus Induces High Magnitude and Breadth of Antibody Responses and Provides Complete Protection In Vivo

Immunogens mimicking the native-like structure of surface-exposed viral antigens are considered promising vaccine candidates. Influenza viruses are important zoonotic respiratory viruses with high pandemic potential. Recombinant soluble hemagglutinin (HA) glycoprotein-based protein subunit vaccines...

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Bibliographic Details
Main Authors: Sneha Raj, Preeti Vishwakarma, Shikha Saxena, Varun Kumar, Ritika Khatri, Amit Kumar, Mrityunjay Singh, Surbhi Mishra, Shailendra Asthana, Shubbir Ahmed, Sweety Samal
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Vaccines
Subjects:
influenza
vaccine
hemagglutinin
intradermal route
virus
Online Access:https://www.mdpi.com/2076-393X/11/4/780

Internet

https://www.mdpi.com/2076-393X/11/4/780

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