Disruption of O-GlcNAc cycling by deletion of O-GlcNAcase (Oga/Mgea5) changed gene expression pattern in mouse embryonic fibroblast (MEF) cells

Adding a single O-GlcNAc moiety to a Ser/Thr molecule of a protein by O-GlcNAc transferase and transiently removing it by O-GlcNAcase is referred to as O-GlcNAc cycling (or O-GlcNAcylation). This O-GlcNAc modification is sensitive to nutrient availability and also shows cross talk with phosphorylati...

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Bibliographic Details
Main Author: Chithra Keembiyehetty
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Genomics Data
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015000604