LncRNA-DANCR Interferes With miR-125b-5p/HK2 Axis to Desensitize Colon Cancer Cells to Cisplatin vis Activating Anaerobic Glycolysis

LncRNA-DANCR Interferes With miR-125b-5p/HK2 Axis to Desensitize Colon Cancer Cells to Cisplatin vis Activating Anaerobic Glycolysis

Colon cancer is one of the most prevalent malignancies that lead to high occurrence of cancer-related deaths. Currently, chemotherapies and radiotherapies remain the primary treatments for advanced colon cancer. Despite the initial effectiveness, a fraction of colon cancer patients developed cisplat...

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Bibliographic Details
Main Authors: Huijuan Shi, Kejun Li, Jinxin Feng, Gaojie Liu, Yanlin Feng, Xiangliang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
lncRNA-DANCR
colon cancer
microRNA-125b-5p
hexokinase 2
cisplatin resistance
glycolysis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01034/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01034/full

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