Chitosan Derivatives with Mucoadhesive and Antimicrobial Properties for Simultaneous Nanoencapsulation and Extended Ocular Release Formulations of Dexamethasone and Chloramphenicol Drugs

Chitosan Derivatives with Mucoadhesive and Antimicrobial Properties for Simultaneous Nanoencapsulation and Extended Ocular Release Formulations of Dexamethasone and Chloramphenicol Drugs

The aim of this work was to evaluate the effectiveness of neat chitosan (CS) and its derivatives with 2-acrylamido-2-methyl-1-propanesulfonic acid (AAMPS) and [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide (MEDSP) as appropriate nanocarriers for the simultaneous ocular administ...

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Bibliographic Details
Main Authors: Aikaterini Karava, Maria Lazaridou, Stavroula Nanaki, Georgia Michailidou, Evi Christodoulou, Margaritis Kostoglou, Hermis Iatrou, Dimitrios N. Bikiaris
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceutics
Subjects:
chitosan
derivatives
mucoadhesion
antimicrobial activity
ocular release
nanoencapsulation
Online Access:https://www.mdpi.com/1999-4923/12/6/594

Internet

https://www.mdpi.com/1999-4923/12/6/594

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