Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment

Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment

Summary: Membrane lipids and their metabolism have key functions in neurotransmission. Here we provide a quantitative lipid inventory of mouse and rat synaptic junctions. To this end, we developed a multiomics extraction and analysis workflow to probe the interplay of proteins and lipids in synaptic...

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Bibliographic Details
Main Authors: Maximilian Borgmeyer, Cristina Coman, Canan Has, Hans-Frieder Schött, Tingting Li, Philipp Westhoff, Yam F.H. Cheung, Nils Hoffmann, PingAn Yuanxiang, Thomas Behnisch, Guilherme M. Gomes, Mael Dumenieu, Michaela Schweizer, Michaela Chocholoušková, Michal Holčapek, Marina Mikhaylova, Michael R. Kreutz, Robert Ahrends
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Cell Reports
Subjects:
Lipidomics
synaptic junctions
endocannabinoid signaling
multiomics
enriched environment
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721012572

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http://www.sciencedirect.com/science/article/pii/S2211124721012572

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