Impaired Gut–Systemic Signaling Drives Total Parenteral Nutrition-Associated Injury

Impaired Gut–Systemic Signaling Drives Total Parenteral Nutrition-Associated Injury

Background: Total parenteral nutrition (TPN) provides all nutritional needs intravenously. Although lifesaving, enthusiasm is significantly tempered due to side effects of liver and gut injury, as well as lack of mechanistic understanding into drivers of TPN injury. We hypothesized that the state of...

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Bibliographic Details
Main Authors: Miguel Guzman, Chandrashekhara Manithody, Joseph Krebs, Christine Denton, Sherri Besmer, Pranjali Rajalakshmi, Sonali Jain, Gustavo Adolfo Villalona, Ajay Kumar Jain
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Nutrients
Subjects:
parenteral nutrition
liver disease
gut injury
gut–systemic crosstalk
hepato-biliary receptors and transporters
Online Access:https://www.mdpi.com/2072-6643/12/5/1493

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https://www.mdpi.com/2072-6643/12/5/1493

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