Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation

Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation

Abstract Microglia nodules (HLA-DR+ cell clusters) are associated with brain pathology. In this post-mortem study, we investigated whether they represent the first stage of multiple sclerosis (MS) lesion formation. We show that microglia nodules are associated with more severe MS pathology. Compared...

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Bibliographic Details
Main Authors: Aletta M. R. van den Bosch, Marlijn van der Poel, Nina L. Fransen, Maria C. J. Vincenten, Anneleen M. Bobeldijk, Aldo Jongejan, Hendrik J. Engelenburg, Perry D. Moerland, Joost Smolders, Inge Huitinga, Jörg Hamann
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46068-3

Internet

https://doi.org/10.1038/s41467-024-46068-3

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